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Increased sugar uptake promotes oncogenesis via EPAC/RAP1 and O-GlcNAc pathways

    ura soul
    by ura soul
    Increased sugar uptake promotes oncogenesis via EPAC/RAP1 and O-GlcNAc pathways
    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3871217/

    There is a considerable resurgence of interest in the role of aerobic glycolysis in cancer; however, increased glycolysis is frequently viewed as a consequence of oncogenic events that drive malignant cell growth and survival. Here we provide evidence ...

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